Instead, youll start by receiving just one treatment course of Injectafer. They can give you tips on how to deal with any side effects that may be bothersome. As with most drugs, some people can have an allergic reaction after taking Injectafer. (One treatment course includes two doses of the drug.) Should I avoid certain foods while taking Venofer Vial? There may be risks to the mother and fetus associated with untreated IDA in pregnancy. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. For additional information, contact your healthcare provider. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Does Venofer Vial interact with other drugs you are taking? Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Some products that may interact with this drug include: vitamin products, other iron-containing products. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Notify your healthcare provider of any irritation at the injection site. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Find out what health conditions may be a health risk when taken with Venofer Vial No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Do not double the dose to catch up. Side effectsare uncomfortable reactions to medications or drugs. There may be drug take-back programs in your area. * Feraheme has a boxed warning for this side effect. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. treatment schedule in further detail. Talk to your pharmacist for more details. But for other people, their IDA returns after treatment with Injectafer. Its given by either intravenous (IV) infusion or slow IV injection. Venofer® (iron sucrose injection, USP) is available by prescription only. Below are examples of these side effects. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. <> xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? wAd**CgI%"nn{Oa[q{r5 Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. The drug helps increase your hemoglobin level back to a value thats within the normal range. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Together, they can recommend ways to help you manage a body weight thats healthy for you. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. This website is intended for use by US healthcare professionals only. I actually was constipated after my 3rd but didn't think anything of it. Yes, in some cases it may. With anemia, you have a low level of red blood cells (RBCs) in your body. Some drugs may have another patient information leaflet. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Brand-name medications usually cost more than generics. With this condition, you also have a low hemoglobin level. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. Use of the term female in this article refers to sex assigned at birth. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. The information provided is not intended to replace your healthcare provider's medical advice. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Its possible that after getting two doses of Injectafer, your anemia may go away completely. During Injectafer treatment, your doctor will likely order blood tests. Nose or throat irritation. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. How long does iron infusion stay in your system? Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. No, you most likely wont take Injectafer long term. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Answer by DrLact: About Venofer usage in lactation. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Learn how to store and discard medical supplies safely. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. This survey is being conducted by the WebMD marketing sciences department. All rights reserved. Do not exceed 1,500 mg of iron per dosing course. With IDA, you have low hemoglobin levels. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Its responsible for carrying oxygen throughout your body. If either is present, do not use the liquid. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. It can be given as a slow injection over 2 to 5 minutes or as an infusion. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. Keep all medications away from children and pets. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. If youre interested in finding an alternative to Injectafer, talk with your doctor. Low iron saturation, or iron deficiency, has various possible causes. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Evenbirth controlcan lead to severeside effectslike bloodclots. Its not known if Injectafer is safe to take during pregnancy. Discuss the risks and benefits with your doctor. endobj If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. 4 0 obj Tell your doctor if you are taking iron supplements or other iron-based oral medications. Learn how to store and discard medical supplies safely. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Before using, check this product visually for particles or discoloration. Tell all of your health care providers that you take Venofer. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. An LSD comedown is when the mental and hallucinatory effects have worn . Heres some detail on certain side effects this drug may cause. Call your doctor right away if you have serious side effects. People from different ethnic backgrounds process medications differently. Injectafer infusions are given over a period of at least 15 minutes. They can recommend if this is safe for you to do. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. 1 0 obj reactions at the site of the injection. If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Diarrhea. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. With slow IV injection, the drug is given as a single, slow injection into your vein. (A generic drug is an exact copy of the active drug in a brand-name medication.) Phosphorus also helps your nerves function properly. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. With IV infusion, the drug is given as a slow drip into your vein over a period of time. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. 3 0 obj In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. This is not a complete list of side effects and others may occur. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). Talk with the doctor. 2. Pain, swelling, or redness at the injection site may occur. Call your doctor for medical advice about side effects. Injectafer is approved to treat iron deficiency anemia (IDA). So theres no recommended pediatric dosage for Injectafer. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Throw away unused or expired drugs. As with all medications, the cost of Injectafer can vary. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. Learn more about these, as well as the symptoms, diagnosis, and treatments. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Storage Condition Store in a cool and dry place protected from light. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Its caused by your body not having enough iron, which is needed to make hemoglobin. But its only approved for use in people with CKD who may or may not need dialysis. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. The study also didnt show if one treatment was worse than the other. Someside effectsare temporary or last as long as the person continues takingprescription medicine. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. Many people using this medication do not have serious side effects. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Copyright 1996-2023 Cerner Multum, Inc. Keep all drugs out of the reach of children and pets. Last updated on Feb 20, 2023. Venofer is for use in adults and children at least 2 years old. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Canada residents can call a provincial poison control center. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. Also tell them about any vitamins, herbs, and supplements you use. other treatments you receive, you will need to go back for several treatments with Venofer. Not all possible drug interactions are listed here. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Your doctor will determine the best dosage to fit your needs. Venofer treatment may be repeated if iron deficiency reoccurs. Mild side effects of Injectafer can include:*. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Iron infusion side effects vary depending on which form is being used. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Venofer may cause significant hypotension (decreased blood pressure). If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. endobj Iron infusion benefits. And this person had gotten their first dose of the drug without having an allergic reaction. . Do not start, stop, or change the dosage of any medicines without your doctor's approval. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. A healthcare provider will give you this injection. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Here we look at how Injectafer and Venofer are alike and different. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). With IV infusion, the drug is given as a slow drip into your vein over a period of time. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. (A class of medications describes a group of drugs that work in the same way.). Injectafer helps to treat IDA by providing an iron infusion directly into your body. The Injectafer dosage your doctor prescribes will depend on your body weight. This includes your doctors, nurses, pharmacists, and dentists. The following information is provided for clinicians and other healthcare professionals. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ Follow your doctor's directions carefully. Side effects like nausea and low blood pressure are common with most iron infusions. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Injectafer and Feraheme are both brand-name drugs. Very bad and sometimes deadly allergic side effects have rarely happened. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Consult your doctor before breast-feeding. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. weakness. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Last reviewed . This can be very helpful in . There are different types of anemia, but IDA is the most common type. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. If you notice other effects not listed above, contact your doctor or pharmacist. The researchers looked to see how well each drug worked to increase peoples hemoglobin level. Why is the range so wide? 2 0 obj Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. They have been a god send. Injectafer should be stored between 68F to 77F (20C to 25C). It may also cause nervousness, restlessness, and difficulty sleeping in some people. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. Most people will metabolize medication by half every time it circulates the body. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. You may need extra iron because of blood loss during kidney dialysis. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. If you have questions about side effects, call your doctor. Details. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. ByDr. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. There isnt a known interaction between Injectafer and alcohol. Understanding what thoseside effectsare can lead to a strategy to prevent them. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Call your doctor for instructions if you miss an appointment for your Venofer injection. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. One of the most commonly used tests to monitor IDA is the hemoglobin test. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. These pregnancy-related problems include preterm delivery and low birth weight of your infant. What is the latest research on the form of cancer Jimmy Carter has? Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; This medication passes into breast milk. There are currently no generic forms of either drug. Be ready to tell or show what was taken, how much, and when it happened. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. This allows them to manage any side effects that you may have following your dose. These side effects can range from being mild to severe. The benefit of treating your condition during pregnancy may outweigh any risks. You will need to talk about the benefits and risks to you and the baby. Learn about the causes, symptoms, diagnosis, and treatment of this. Some people only need one treatment course of Injectafer. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. generalized weakness. I had Venofer infusions, 2 rounds now in the span of three years. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Call your doctor for medical advice about side effects. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. This is not a list of all drugs or health problems that interact with this medicine. (Hemoglobin is a protein thats found inside your red blood cells.). Is the ketogenic diet right for autoimmune conditions? I used to get a different type but my . This information is not specific medical advice and does not replace information you receive from the healthcare provider. However, consuming large amounts of alcohol can actually cause anemia in some people. But so far I feel better than before the infusion. Venofer is not for treating other forms of anemia not caused by iron deficiency. (Hemoglobin is a protein thats found in your red blood cells.). Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Potential injection site discoloration has happened. %PDF-1.3 <> These people may lose weight as their anemia improves because theyre more active. And these two doses need to be separated by at least 7 days. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. pain in the arms or legs. 5 0 obj You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA).
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